Irinotecan-encapsulated double-reverse thermosensitive nanocarrier system for rectal administration
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Irinotecan Suppository for Rectal Administration
Irinotecan suppository was prepared using the moulding method with a homogeneous blend. A sensitive and specific fluorescence method was developed and validated for the determination of irinotecan in plasma using HPLC. The pharmacokinetics of intravenous administered and rectal administered in rabbits was investigated. Following a single intravenous dose of irinotecan (50 mg/kg), the plasma iri...
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ژورنال
عنوان ژورنال: Drug Delivery
سال: 2017
ISSN: 1071-7544,1521-0464
DOI: 10.1080/10717544.2016.1272651